NO.1 BEAUTY# Advances in Medicinal Chemistry: 4 Reviews Best Buy price

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Advances in Medicinal Chemistry: 4


31QrpHWvbvL - NO.1 BEAUTY# Advances in Medicinal Chemistry: 4 Reviews  Best Buy price
Volume four of Advances in Medicinal Chemistry is comprised of 6 chapters on a large range of topics in medicinal chemistry, inclusive molecular modeling, constitution-based drug design, natural synthesis, peptide conformational research, organic assessment, constitution-activity correlation, and lead optimization. Chapter 1 presents an account about amino acid-based peptide mimetics corresponding to b-turn, loop, helical motifs in proteins as a probe of ligand-receptor and ligand-enzyme molecular interactions. Chapter two addresses new facets of the medicinal chemistry of the essential anticancer drug Taxol® (paclitaxel). Chapter three relates an account of the search for new drugs for the therapy of malaria based on the natural product artemisinin. Chapter four applies computational chemistry towards the evaluation of compound libraries for organic testing. Chapter five describes the construction of a three-dimensional molecular model of the human thrombin receptor, the 1st protease-activated G-protein coupled receptor (PAR-1), as a means to discover the intermolecular contacts involved in agonist peptide recognition. Ultimately, Chapter six describes the investigation conducted at Merck on inhibitors of farnesyl transferase as a possibility therapy for human cancers.
Volume four of Advances in Medicinal Chemistry is comprised of 6 chapters on a large range of topics in medicinal chemistry, inclusive molecular modeling, constitution-based drug design, natural synthesis, peptide conformational research, organic assessment, constitution-activity correlation, and lead optimization. Chapter 1 presents an account about amino acid-based peptide mimetics corresponding to b-turn, loop, helical motifs in proteins as a probe of ligand-receptor and ligand-enzyme molecular interactions. Chapter two addresses new facets of the medicinal chemistry of the crucial anticancer drug Taxol® (paclitaxel). Chapter three relates an account of the search for new drugs for the therapy of malaria based on the natural product artemisinin. Chapter four applies computational chemistry towards the evaluation of compound libraries for organic testing. Chapter five describes the construction of a three-dimensional molecular model of the human thrombin receptor, the 1st protease-activated G-protein coupled receptor (PAR-1), as a means to discover the intermolecular contacts involved in agonist peptide recognition. Ultimately, Chapter six describes the investigation conducted at Merck on inhibitors of farnesyl transferase as a possibility therapy for human cancers.

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